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Radiobiology has had a pivotal role in the safe delivery of ionising radiation for decades and continues to feed our understanding of both tumour response and normal tissue toxicity for decades. With the advent of greater technological capability to deliver photon dose distributions with both greater conformity and precision (through IMRT, VMAT, IGRT and SRS/SBRT) and also with the availability of other modalities (such as proton beam therapy), changes to dose, fractionation and overall treatment time are now more possible than ever, but still require a solid understanding of both likely tumour response and normal tissue toxicity especially in clinical practice for aspects like treatment interruptions and re-treatment tolerances, especially with respect to experiences during the COVID19 pandemic. Radiobiology has a key voice to contribute to a solid understanding in these discussions and changes, alongside robust clinical trials, in order to deliver such modern treatments with optimum safety and efficacy.

This virtual event brought together world experts in giving a refresher for up-to-date key radiobiological principles underlying conventional and modern, altered delivery patterns; and also for practical experience of its use in treatment interruptions, re-treatment tolerances and radiobiologically optimised treatment planning. It was also a teaching opportunity for radiobiological understanding for the newer treatments which encompass a change in modality and delivery (e.g. particle therapy and dose rate effects).

The teaching faculty have worldwide expertise in Radiobiological research and understanding in clinical Radiotherapy practice. They are:

• Prof Bleddyn Jones, University of Oxford
• Prof Roger Dale, Imperial College, London
• Prof John Hopewell, University of Oxford
• Dr Jason Parsons, University of Liverpool
• Prof Alan Nahum

This event was chaired by Mike Kirby.

4 CPD points

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Duration:247 mins